Literature summary extracted from

Liu, J.; Huang, C.; Peng, C.; Xu, F.; Li, Y.; Yutaka, Y.; Xiong, B.; Yang, X.
Stromal fibroblast activation protein alpha promotes gastric cancer progression via epithelial-mesenchymal transition through Wnt/ beta-catenin pathway (2018), BMC Cancer, 18, 1099 .

Application

EC Number	Application	Comment	Organism
3.4.21.B28	medicine	fibroblast activation protein alpha has a high-risk correlation with the malignant level of clinical outcomes in gastric cancer patients	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.21.B28	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.21.B28	fibroblast	cancer-associated	Homo sapiens	-
3.4.21.B28	gastric cancer cell line	-	Homo sapiens	-
3.4.21.B28	GES-1 cell	-	Homo sapiens	-
3.4.21.B28	HELF cell	-	Homo sapiens	-
3.4.21.B28	lung fibroblast	embryonic	Homo sapiens	-
3.4.21.B28	SGC-7901 cell	-	Homo sapiens	-

Synonyms

EC Number	Synonyms	Comment	Organism
3.4.21.B28	fibroblast activation protein alpha	-	Homo sapiens

General Information

EC Number	General Information	Comment	Organism
3.4.21.B28	physiological function	the enzyme promotes the ability of proliferation, migration, invasion, apoptosis-inhibition of SGC7901 cells and induces apoptosis of GES1 cells in vitro	Homo sapiens

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Release 2023.1 (January 2023)